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Trimine 25mg Tablet

Prescription Required

Product introduction

Trimine 25mg Tablet is known as a tricyclic antidepressant. It is used to treat depression and bedwetting in children of age 6 years and above. It is also effective in treating depression that is unresponsive to other treatments.

Trimine 25mg Tablet works by increasing the levels of chemical messengers in the brain that stabilizes and enhances the mood. It is better to take it before bedtime because it can make you feel drowsy. It can be taken with or without food, but you should take it at a fixed time each day for better efficacy. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed any dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to the doctor. Your dose may be modified or gradually decreased before stopping the medication.

The most common side effects of this medicine include increased heart rate, blurred vision, dryness in the mouth, difficulty in urination, and constipation. Initially, this medicine may also cause a sudden drop in blood pressure, especially when you change positions. It may even cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you. To lower the chances of dizziness, rise slowly if you have been sitting or lying down. It may also lead to weight gain in some people. Most of the common side effects tend to be mild and temporary. Your doctor may be able to suggest ways of preventing or reducing side effects if they bother you or do not go away. Serious side effects associated with this medicine are rare.

Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same or any other diseases. Pregnant and breastfeeding women should take this medicine with proper consultation and caution. This medicine is not known to be addictive, but you can experience additional side effects (withdrawal symptoms) if you stop taking it suddenly. If you notice any sudden mood change or get suicidal or self-harm thoughts, you must consult the doctor without delay. Also, remember to take this medicine as advised by the doctor as an overdose of this medication may lead to a serious health emergency. Consumption of alcohol should be avoided as alcohol interacts with this medicine to cause serious health issues.

Uses of Trimine Tablet

Benefits of Trimine Tablet

In Depression

Trimine 25mg Tablet is thought to work by affecting the balance of certain chemicals (such as serotonin) in the brain. It helps improve mood and feelings of wellbeing, relieve anxiety and tension, help you sleep better, and increase your energy level. It is used to treat depression that is unresponsive to other medicines. You need to take it regularly as it is prescribed for it to be most effective and should not stop taking it suddenly.

In Bed-wetting

Bed-wetting is a condition that is seen in children who are old enough to control their urine at night during sleep but fail to do so. Trimine 25mg Tablet can help your child control nighttime bed-wetting. Trimine 25mg Tablet works by blocking the effect of a certain natural substance (acetylcholine) on the bladder muscles. This prevents bladder overflow at night. However, this medicine is used for managing bed-wetting only during the night and should not be used in children younger than 6 years of age.

Side effects of Trimine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Trimine

  • Increased heart rate
  • Blurred vision
  • Dryness in mouth
  • Difficulty in urination
  • Constipation
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)

How to use Trimine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trimine 25mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Trimine Tablet works

Trimine 25mg Tablet is a tricyclic antidepressant. It increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression.

Safety advice

Alcohol
UNSAFE
Trimine 25mg Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Trimine 25mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Trimine 25mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Trimine 25mg Tablet may cause side effects which could affect your ability to drive.
As Trimine 25mg Tablet may impair your alertness or cause drowsiness or blurred vision, and this may affect your ability to drive.
Kidney
CAUTION
Trimine 25mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Trimine 25mg Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Trimine 25mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Trimine 25mg Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is recommended while you are taking this medicine.

What if you forget to take Trimine Tablet?

If you miss a dose of Trimine 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Trimine 25mg Tablet
₹0.43/Tablet
₹0.65/tablet
51% costlier
Antidep 25mg Tablet
Torrent Pharmaceuticals Ltd
₹0.66/tablet
53% costlier
Depsol 25mg Tablet
Intas Pharmaceuticals Ltd
₹0.58/tablet
35% costlier
Depranil 25mg Tablet
La Pharmaceuticals
₹0.44/tablet
2% costlier
Impramine 25mg Tablet
Sun Pharmaceutical Industries Ltd
₹0.35/tablet
19% cheaper

Quick tips

  • Trimine 25mg Tablet is used for the treatment of depression and bedwetting in children.
  • The main dose should be taken at night as this medicine may produce drowsiness or sleepiness.
  • You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood.
  • Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine. 
  • Do not drive or do anything that requires concentration until you know how this medicine affects you.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Dibenzazepines Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Tricyclic antidepressants

Patient concerns

arrow
Bed wetting every night help pl Any medicine for bed wetting
Dr. Gopal Samdani
Paediatrics
There are many underlying causes of your symptoms. Specific treatment can not be given unless we establish exact underlying cause. Please consult Pediatrician. will take detail history and will examine your child in detail. At time may ask you relevant investigations if necessary. All information will be used to determine exact underlying cause of problem. Depending upon cause will prescribe you treatment.
Bed wetting i.e.urine at bed during night
Dr. Praveen Pushkar
Urology
U need to see paediatrician near by
arrow

FAQs

What is Trimine 25mg Tablet used for?

Trimine 25mg Tablet is mainly used to treat depression. It is also used to treat bed wetting in children older than 6 years of age. It works by restoring the chemical imbalance in the brain, thereby enhancing mood and behavior.

What are the side effects of Trimine 25mg Tablet?

Trimine 25mg Tablet may cause side effects like increased heart rate, blurred vision, dryness in mouth, difficulty in urination, constipation and orthostatic hypotension (sudden decrease in blood pressure on standing). Consult your doctor if these side effects do not go away or worry you.

Can I just stop taking Trimine 25mg Tablet?

No, you must not stop taking Trimine 25mg Tablet suddenly even if you are feeling good as it may worsen your condition. Continue taking Trimine 25mg Tablet for the duration prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.

Can a pregnant woman take Trimine 25mg Tablet?

No, pregnant women should avoid taking Trimine 25mg Tablet, unless recommended by the doctor. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved. Taking this medicine during the last trimester of the pregnancy may cause symptoms such as breathing problems, weakness, irritability, changes in blood pressure, tremors, and spasms in the newborn. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding.

Does Trimine 25mg Tablet make you sleepy?

Yes, Trimine 25mg Tablet may make you feel sleepy. Therefore, it is advised that you should not drive, use any heavy machinery or do any work that requires concentration while taking Trimine 25mg Tablet. Also, refrain from taking alcohol if you are being treated with Trimine 25mg Tablet as it will increase your drowsiness.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Stahl SM, editor. Imipramine. In: Stahl's Essential Pschopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 307-12.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 697.
  3. Drugs.com. Imipramine Pregnancy and Breastfeeding Warnings. [Accessed 25 Mar. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004;80(5):4-6. [Accessed 20 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:External Link
Country of origin: India

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