Author Details
Written By
BDS
Reviewed By
DM, MD
Last updated
08 Apr 2022 | 05:11 PM (IST)

We provide you with authentic, trustworthy and relevant information

Want to know more

Have issue with the content?

Report Problem

Valparin 400mg Injection

Prescription Required
SALT COMPOSITION

Product introduction

Valparin 400mg Injection is used for the treatment of epilepsy (seizures). It controls seizures by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Valparin 400mg Injection is given under the supervision of a healthcare professional and should not be self-administered. You should never skip any doses and finish the full course of treatment even if you feel better as stopping the medication without talking to the doctor may cause non-stop seizures and can endanger life. Be careful if you are using birth control pills as this medicine may interfere with the working of contraceptives.

Common side effects of this medicine include headache, nausea, dizziness, and sleepiness, constipation, and weight gain among others. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects. Long-term treatment can cause weakness in your bones (osteoporosis), increasing your risk of breaking a bone.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression, or suicidal thoughts. Also let your healthcare team know about all other medications you are using as some may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, this medicine can be taken if clearly needed but the dose may be adjusted. You may need frequent blood tests to check how you are responding to this medicine.

Uses of Valparin Injection

Benefits of Valparin Injection

In Epilepsy/Seizures

Valparin 400mg Injection is an anticonvulsant (or anti-epileptic) medicine that works by decreasing the nerve impulses which cause the seizures. By controlling the frequency of seizures, it will help you go about your daily activities with more confidence. It helps reduce symptoms such as confusion, uncontrollable jerking movements, loss of awareness, and fear or anxiety.
This medicine is not associated with any physical or psychological dependence (addiction) but it should not be stopped suddenly. It is given by your healthcare provider and should not be self-administered. It must be taken regularly as prescribed to be effective. Missing doses may trigger a seizure.

Side effects of Valparin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Valparin

  • Dizziness
  • Blurred vision
  • Nausea1a
  • Vomiting
  • Sleepiness
  • Hair loss
  • Weight gain
  • Tremor
  • Double vision
  • Weakness
  • Stomach pain
  • Increased appetite

How to use Valparin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Valparin Injection works

Valparin 400mg Injection is an antiepileptic medication. It controls seizures or fits by decreasing the abnormal and excessive activity of the nerve cells in the brain.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Valparin 400mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Valparin 400mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Valparin 400mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Monitor the baby for unusual bruising or bleeding, jaundice and other signs of liver damage.
Driving
UNSAFE
Valparin 400mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Valparin 400mg Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Valparin 400mg Injection may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Valparin 400mg Injection should be used with caution in patients with liver disease. Dose adjustment of Valparin 400mg Injection may be needed. Please consult your doctor.
Use of Valparin 400mg Injection is not recommended in patients with the severe liver disease.

What if you forget to take Valparin Injection?

If you miss a dose of Valparin 400mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Take your medication regularly as directed by your doctor as missing doses can trigger seizures.
  • Do not change the brand of your medicine and make sure that you have sufficient amount of medicine present with you.
  • Some healthy tips to prevent seizures:
    • Practice yoga every day.
    • Get enough sleep at nighttime.
    • Limit the use of screen time such as mobile/laptop.
    • Take your medication on time.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Monitor your weight during treatment with this medicine as it can cause weight gain.
  • It may cause cosmetic side effects such as increased hair growth on face, acne and thinning of hair. Talk to your doctor if this bothers you.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • Do not stop taking the medication suddenly without talking to your doctor as it may increase the seizure frequency.

Fact Box

Chemical Class
Valproic Acid Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS
Action Class
Sodium channel modulators (AED)

Patient concerns

arrow
Sir/Mam, I am PATIENT I have severe migraine problem with seizure disorder.So I take valparin chrono 300mg twice daily which is prescribed by my Doctor. So, now a month I am facing some severe hair fall. My doctor have suggested me Mintop Tropical solution usp 2 and till now I did't see any improvement to my hair. So therefore I would request you can you please help me?
Dr. Vikas Sharma
Neurology
ask to change valparin
Sir I have epilepsy problem I have done course valparin chrono 3 year how long time run course
Dr. Vikas Sharma
Neurology
Can be withdrawn under medical supervision
arrow

FAQs

How is Valparin 400mg Injection administered?

Valparin 400mg Injection is administered by or under the supervision of a healthcare professional or a doctor and should never be self-administered. It may be given slowly into a vein (intravenously) or by infusion using a separate intravenous line in normal saline, dextrose 5%, or dextrose saline. The dose depends on the individual’s age and body weight. Each vial of Valparin 400mg Injection is for single-dose injection only and should be discarded after use.

I have gained weight after I started using Valparin 400mg Injection. Is it because of this medicine? What should I do?

Yes, weight gain can occur with the use of Valparin 400mg Injection. To control your weight, you should have a healthy balanced diet and exercise regularly. Talk to your doctor if you have any other concerns.

Does Valparin 400mg Injection affect the working of birth control pills?

Yes, Valparin 400mg Injection does not have any effect on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Valparin 400mg Injection and seizures may occur. It is important that you inform your doctor that you are using birth control pills. Your doctor will keep a track on your response to the treatment and monitor the Valparin 400mg Injection levels in your blood levels.

Is it safe to take Valparin 400mg Injection for long term?

Many patients can safely take Valparin 400mg Injection for a long time. Rarely, long-term use of Valparin 400mg Injection may weaken your bones, thereby increasing their chances of breaking easily (osteoporosis and osteopenia). If you are taking Valparin 400mg Injection for a long time, get regular check ups done for bone health.

I am concerned because I have heard that Valparin 400mg Injection causes hair loss. Is it true?

Valparin 400mg Injection may cause thinning of hair, change of hair colour and even hair loss. If you are concerned, talk to your doctor if it is possible to reduce the dose of Valparin 400mg Injection. Your hair may regrow after either reducing your dose or switching to a different medicine.

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Drugs.com. Valproic acid Pregnancy and Breastfeeding Warnings. [Accessed 22 Mar. 2019] (online) Available from:External Link
  2. Sodium valportae. Lake Forest, Illinois: Hospira, Inc.; 1996 [revised Jul. 2013]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
Country of origin: India

DISCONTINUED
We do not facilitate sale of this product at present

INDIA’S LARGEST HEALTHCARE PLATFORM

260m+
Visitors
31m+
Orders Delivered
1800+
Cities
Get the link to download App
Reliable

All products displayed on Tata 1mg are procured from verified and licensed pharmacies. All labs listed on the platform are accredited

Secure

Tata 1mg uses Secure Sockets Layer (SSL) 128-bit encryption and is Payment Card Industry Data Security Standard (PCI DSS) compliant

Affordable

Find affordable medicine substitutes, save up to 50% on health products, up to 80% off on lab tests and free doctor consultations.

LegitScript approved
India's only LegitScript and ISO/ IEC 27001:2022 certified online healthcare platform

Know more about Tata 1mgdownArrow

Access medical and health information

Tata 1mg provides you with medical information which is curated, written and verified by experts, accurate and trustworthy. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies.

Order medicines online

Get free medicine home delivery in over 1800 cities across India. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Your safety is our top priority. All products displayed on Tata 1mg are procured from verified and licensed pharmacies.

Book lab tests

Book any lab tests and preventive health packages from certified labs and get tested from the comfort of your home. Enjoy free home sample collection, view reports online and consult a doctor online for free.

Consult a doctor online

Got a health query? Consult doctors online from the comfort of your home for free. Chat privately with our registered medical specialists to connect directly with verified doctors. Your privacy is guaranteed.