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Xmet-Trio 2mg/500mg/0.2mg Tablet


Introduction of Xmet-Trio Tablet

Xmet-Trio 2mg/500mg/0.2mg Tablet belongs to a category of medicines known as anti-diabetic drugs. It is a combination of medicines used to treat type 2 diabetes mellitus in adults. It helps control blood sugar levels in people with diabetes.

Xmet-Trio 2mg/500mg/0.2mg Tablet should be taken with food. Take it regularly at the same time each day to get the most benefit. Your doctor will decide what dose is best for you and this may change from time to time according to how it is working according to your blood sugar levels.

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

The most common side effect of Xmet-Trio 2mg/500mg/0.2mg Tablet is low blood glucose levels (hypoglycemia). Make sure you recognize the signs of having low blood glucose levels, such as sweating, dizziness, headache, and shaking and know how to deal with it. To prevent this, it's important to have regular meals and always carry a fast-acting source of glucose such as sugary food or fruit juice with you. Drinking alcohol can also increase your risk of low blood sugar levels and should be avoided. Other side effects that may be seen on taking this medicine include taste changes, nausea, diarrhea, stomach pain, headache, edema (swelling), blurred vision, bone fracture, and upper respiratory tract infection. Some people may find that they put on weight with this medicine.

You should not take it if you have type 1 diabetes mellitus, if you have diabetic ketoacidosis (high levels of acid in your blood), or if you have severe kidney or liver disease. Before taking this medicine, tell your doctor if you have ever had heart disease. It may not be suitable. Pregnant or breastfeeding women should also consult their doctor before taking it. Your blood sugar levels should be checked regularly and your doctor may also advise blood tests to monitor your blood cell counts and liver function.

Side effects of Xmet-Trio Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xmet-Trio

  • Hypoglycemia (low blood glucose level)
  • Nausea
  • Diarrhea
  • Taste change
  • Flatulence
  • Stomach pain
  • Headache
  • Skin rash
  • Respiratory tract infection

How to use Xmet-Trio Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xmet-Trio 2mg/500mg/0.2mg Tablet is to be taken with food.

How Xmet-Trio Tablet works

Xmet-Trio 2mg/500mg/0.2mg Tablet is a combination of three antidiabetic medicines: Glimepiride, metformin and voglibose. They work by different mechanisms to provide better control of blood sugar when single or dual therapy is not effective. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas to lower the blood glucose. Metformin is a biguanide which lowers glucose production in the liver, delays glucose absorption from intestines and increases the body's sensitivity to insulin. Voglibose is an alpha-glucosidase inhibitor which prevents breakdown of complex sugars into simple sugars such as glucose. This prevents the blood glucose levels from rising to very high levels after meals.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Xmet-Trio 2mg/500mg/0.2mg Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Xmet-Trio 2mg/500mg/0.2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Xmet-Trio 2mg/500mg/0.2mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Xmet-Trio 2mg/500mg/0.2mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Xmet-Trio 2mg/500mg/0.2mg Tablet may be needed. Please consult your doctor.
Use of Xmet-Trio 2mg/500mg/0.2mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Xmet-Trio 2mg/500mg/0.2mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Xmet-Trio 2mg/500mg/0.2mg Tablet may be needed. Please consult your doctor.
Xmet-Trio 2mg/500mg/0.2mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Xmet-Trio 2mg/500mg/0.2mg Tablet
₹6.85/Tablet
Vogli-GM 2 Tablet
Medley Pharmaceuticals
₹8.95/tablet
31% costlier
GV Forlin 2 mg/500 mg/0.2 mg Tablet
Lincoln Pharmaceuticals Ltd
₹4.4/tablet
36% cheaper
₹7.89/tablet
15% costlier
GMM V 2mg/500mg/0.2mg Tablet
El-Dorado Bio-Tech Pvt Ltd
₹6.5/tablet
5% cheaper
Trivofid 2 Tablet
Fidelity Lifesciences Pvt Ltd
₹5/tablet
27% cheaper

Quick tips

Xmet-Trio Tablet

  • Take it with food to lower your chance of having an upset stomach.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal. Carry a sugar source with you for immediate relief.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).

Fact Box

Habit Forming
No
Therapeutic Class
ANTI DIABETIC

Patient concerns

Patient concerns

arrow
My father is a BP patient, taking medicine of Telmisartan-40mg + Chlorthalidone6.25mg. But his BP is not control, i.e. 165/98- so what should I do and what medicine is needed to take for my father???
Dr. Saurabh Arora
Cardiology
Can change to tsaart trio after consulting with your physician
I was taking OLMEZEST H 40 BUT MY BP REMAINS 150/95.I CONSULTED MY DOCTOR AFTER ALL THE TESTS he prescribed OLMEZEST CH 40 .TESTS ARE ALL NORMAL BUT BP IS STILL SAME
Dr. Saurabh Arora
Cardiology
Can try olkem trio after discussing with you r physician
arrow

User feedback


FAQs

Xmet-Trio Tablet

What is Xmet-Trio 2mg/500mg/0.2mg Tablet?

Xmet-Trio 2mg/500mg/0.2mg Tablet is a combination of three medicines: Glimepiride, Metformin and Voglibose. This medicine is used in the treatment of type 2 diabetes mellitus (DM). It improves the blood glucose levels in adults when taken along with proper diet and regular exercise. Glimepiride lowers the blood glucose levels by increasing the release of insulin from the pancreas. Metformin works by lowering the glucose production in the liver and improving insulin sensitivity. Voglibose is an alpha-glucosidase inhibitor which lowers the postprandial (after meals) glucose levels in the body. This combination is not indicated for the treatment of Type 1 DM.

What are the possible side effects of Xmet-Trio 2mg/500mg/0.2mg Tablet?

The use of Xmet-Trio 2mg/500mg/0.2mg Tablet is associated with common side effects like hypoglycemia (low blood sugar level), nausea, diarrhea, altered taste, flatulence, stomach pain, headache, skin rash and respiratory tract infection.

Are there any specific conditions in which Xmet-Trio 2mg/500mg/0.2mg Tablet should not be taken?

The use of Xmet-Trio 2mg/500mg/0.2mg Tablet should be avoided in patients with known allergy to any of the components or excipients of this medicine. The use of this medicine is also avoided in patients with moderate to severe kidney disease and in patients with inflammatory bowel disease, colonic ulcerations and underlying metabolic acidosis including diabetic ketoacidosis.

Is it safe to take alcohol while I am also taking Xmet-Trio 2mg/500mg/0.2mg Tablet?

No, it is not safe to take Xmet-Trio 2mg/500mg/0.2mg Tablet along with alcohol. It may lower your low blood sugar levels (hypoglycemia) and can increase the chances of lactic acidosis.

Can the use of Xmet-Trio 2mg/500mg/0.2mg Tablet cause hypoglycemia?

Yes, the use of Xmet-Trio 2mg/500mg/0.2mg Tablet can cause hypoglycemia (low blood sugar level). Symptoms of hypoglycemia include nausea, headache, irritability, hunger, sweating, dizziness, fast heart rate, and feeling anxious or shaky. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, regular monitoring of blood sugar level is important. Always keep glucose tablets, honey or fruit juice with you.

What are the instructions for the storage and disposal of Xmet-Trio 2mg/500mg/0.2mg Tablet?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Metformin Hydrochloride (SR), Glimepiride & Voglibose. Dehradun, India: Windlas Biotech Private Limited; 2017. [Accessed 08 Apr. 2019] (online) Available from:External Link
  2. Glimepiride. Bridgewater, New Jersey: Sanofi-Aventis U.S. LLC.; 2009. [Accessed 08 Apr. 2019] (online) Available from:External Link
  3. Metformin hydrochloride. Princeton, New Jersey: Bristol-Myers Squibb Company. [Accessed 08 Apr. 2019] (online) Available from:External Link
  4. Dabhi AS, Bhatt NR, Shah MJ. Voglibose: An Alpha Glucosidase Inhibitor. J Clin Diagn Res. 2013;7(12):3023-7. [Accessed 08 Apr. 2019] (online) Available from:External Link
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Xmet-Trio 2mg/500mg/0.2mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

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