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Last updated
05 Dec 2023 | 06:14 PM (IST)

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Zaxyben 50mg Injection


Product introduction

Zaxyben 50mg Injection is a medicine used to treat high blood pressure associated with tumor of the adrenal glands called Pheochromocytoma. Lowering blood pressure helps to prevent future heart attack and stroke.

Zaxyben 50mg Injection is used to treat high blood pressure due to a tumour that releases substances which increases blood pressure

Uses of Zaxyben Injection

Benefits of Zaxyben Injection

In Hypertension (high blood pressure)

If your blood pressure is controlled you are less at risk of having a heart attack or stroke. Zaxyben 50mg Injection reduces the chances of heart diseases and helps you remain healthier for longer. Take it regularly and make appropriate lifestyle changes, such as eating healthy and staying active, to maximize the effectiveness of this medicine.

How to use Zaxyben Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Safety advice

Alcohol
UNSAFE
Zaxyben 50mg Injection may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Zaxyben 50mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Zaxyben 50mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Zaxyben 50mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Zaxyben 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Zaxyben 50mg Injection may be needed. Please consult your doctor.
Use of Zaxyben 50mg Injection is not recommended in patients with serious kidney disease.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Zaxyben 50mg Injection in patients with liver disease. Please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Zaxyben 50mg Injection
₹1768.7/Injection
Fenoxene 50mg Injection
Samarth Life Sciences Pvt Ltd
₹2384.4/injection
35% costlier
Biophenox 50mg Injection
United Biotech Pvt Ltd
₹1705/injection
4% cheaper

Quick tips

  • Zaxyben 50mg Injection is given as a drip into a vein (intravenous infusion) under the supervision of a doctor.
  • Take it in addition to lifestyle modification with regular exercise, a balanced diet, and smoking cessation.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It may cause dizziness or sleepiness. Do not drive or do anything that requires concentration until you know how it affects you.
  • Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Fact Box

Chemical Class
Phenylmethylamines
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Adrenergic receptor antagonist - non selective

Patient concerns

arrow
I am a patient of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinal condition of high blood pressure. Please see a physician.
Some times I had lot of hypertension
Dr. Jyoti Kapoor Madan
Psychiatry
Hypertension is clinically high blood pressure. Persistent high arterial blood pressure above 120/80 mm HG is termed as pre-hypertension or hypertension, but the point to be emphasized is that this rise in blood pressure is persistent. Transient increase in BP occurs in stress and anxiety and needs to be treated accordingly.
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FAQs

How long should Zaxyben 50mg Injection be taken?

You should take it as long as your doctor has recommended it to you. Do not stop taking it without talking to you doctor first. Long-term use of Zaxyben 50mg Injection is not recommended as cases of developing cancer have been reported. Consult your doctor before starting the treatment.

Who should not use Zaxyben 50mg Injection?

Zaxyben 50mg Injection should not be given to patients who are allergic to it. Additionally, in patients with a recent history (within the last month) of stroke or heart attack, Zaxyben 50mg Injection should be avoided. Tell your doctor if any of these conditions apply to you.

How does Zaxyben 50mg Injection cause tachycardia?

Zaxyben 50mg Injection belongs to alpha receptor blockers class of medicines. Alpha receptors blockade decreases resistance thereby increasing blood flow to the skin, mucosa (membrane that lines various cavities of the body), and abdominal viscera (membrane lining the abdomen). This results in lowering of blood pressure. This reduced blood pressure and increased release of chemical messenger (noradrenaline) results in reflex tachycardia.

Why is Zaxyben 50mg Injection used for pheochromocytoma?

Zaxyben 50mg Injection helps in reducing the increased blood pressure caused by Pheochromocytoma. It is a tumor of the adrenal glands. It causes the release of certain substances (catecholamines) from the adrenal glands into the bloodstream in large quantities, causing high blood pressure. Zaxyben 50mg Injection works by blocking alpha receptors, thereby decreasing blood pressure.

What are the advantages of using Zaxyben 50mg Injection in pheochromocytoma?

Using Zaxyben 50mg Injection in pheochromocytoma is beneficial due to its long duration of action leading to twice daily dosing. Along with that, it prevents episodic increase of catecholamine releases during pre- and post-operative period which helps in keeping the blood pressure under control during surgical procedures.

What are other uses of Zaxyben 50mg Injection?

Zaxyben 50mg Injection is sometimes effective in treating Raynaud’s phenomenon. This condition results in discoloration of the fingers and/or toes after exposure to changes in temperature (cold or hot) or emotional events. Zaxyben 50mg Injection is also useful in treating frostbite.

Can Zaxyben 50mg Injection affect sex life?

Yes, use of Zaxyben 50mg Injection may affect sex life. It may cause inhibition of ejaculation and may make the patient impotent. However, these effects are generally mild and lasts for only a short time. Discuss with your doctor if you experience this.

What are the symptoms of overdose of Zaxyben 50mg Injection?

Taking more than the recommended dose of Zaxyben 50mg Injection may cause significant decrease in blood pressure which may last for several hours, increased heartbeat, and one may even collapse. If you accidentally take an overdose of this medicine, contact your doctor and seek immediate medical help.

How quickly does Zaxyben 50mg Injection work?

The maximum effect of Zaxyben 50mg Injection is attained in about 1 hour after the dose. However, it may take several hours to see the effect after a single oral dose. These effects may persist for 3-4 days.
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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 309-10.
  2. Robertson D, Biaggioni I. Adrenoceptor Antagonist Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 152.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1106-107.

Marketer details

Name: Molekule India Pvt Ltd
Address: CRIMPAGE CORPORATION, 3RD FLOOR, PLOT NO. 57, STREET NO. 17, MIDC, MAROL, ANDHERI (EAST), MUMBAI MH 400093 IN , - , .
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Zaxyben 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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1.0 ml in 1 vial
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