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MDS, BDS
Reviewed By
MD (Pharmacology), MBBS
Last updated
05 Dec 2023 | 06:14 PM (IST)

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Zoladex LA 10.8mg Injection

Prescription Required

Product introduction

Zoladex LA 10.8mg Injection is used for the treatment of prostate cancer in men.

Zoladex LA 10.8mg Injection is used to treat prostate cancer in men and to aid women in getting pregnant and treat endometriosis in women (condition where tissue that normally lines the inside of your womb (uterus) is found elsewhere)

Uses of Zoladex Injection

Benefits of Zoladex Injection

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Zoladex LA 10.8mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Zoladex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zoladex

  • Bone weakness
  • Injection site reactions (pain, swelling, redness)
  • Decreased libido
  • Erectile dysfunction
  • Depression
  • Headache
  • Dizziness
  • Nausea
  • High blood pressure
  • Breast atrophy
  • Pain during sexual intercourse
  • Hot flushes
  • Sexual dysfunction
  • Urinary tract disorder
  • Lethargy
  • Pain
  • Edema (swelling)
  • Upper respiratory tract infection
  • Rash
  • Sweating
  • Decreased appetite
  • Chronic obstructive pulmonary disease (COPD)
  • Heart failure
  • Insomnia (difficulty in sleeping)
  • Vaginal inflammation
  • Emotional lability
  • Acne
  • Breast enlargement
  • Pelvic discomfort
  • Application site reactions (burning, irritation, itching and redness)
  • Pain during periods
  • Uterine bleeding

How to use Zoladex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Zoladex Injection works

Zoladex LA 10.8mg Injection is a synthetic hormone. It works by reducing the level of testosterone (male hormone). This causes regression of prostate tumor and improves symptoms.

Safety advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Zoladex LA 10.8mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Zoladex LA 10.8mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
UNSAFE
Zoladex LA 10.8mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
SAFE
Zoladex LA 10.8mg Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Zoladex LA 10.8mg Injection is safe to use in patients with kidney disease. No dose adjustment of Zoladex LA 10.8mg Injection is recommended.
Liver
SAFE IF PRESCRIBED
Zoladex LA 10.8mg Injection is safe to use in patients with liver disease. No dose adjustment of Zoladex LA 10.8mg Injection is recommended.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Zoladex LA 10.8mg Injection is used in the treatment of prostate cancer.
  • It is a prefilled syringe that is injected under the skin of the abdomen, every 12 weeks.
  • It should not be used in females and children.
  • It may cause a reduction in bone mineral density and weakened bones. Your doctor may prescribe other medicines to reduce bone loss.
  • Inform your doctor if you start to feel depressed or have disturbing thoughts or feelings during treatment with this medicine.
  • Inform your doctor if you suffer from high blood pressure or irregular heartbeat.

Fact Box

Chemical Class
GNRH Analogue
Habit Forming
No
Therapeutic Class
HORMONES
Action Class
GNRH agonists/analogue

Patient concerns

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My Dr. has given dose of inj. Zoladex 3.6 mg for endometriosis, 3 doses of its are compulsory or 2 doses are sufficient, because I have some side effects like sleeping problem, headache and sickness. Please suggest me.
Dr. Megha Gupta
Obstetrics and Gynaecology
Zoladex is a hormonal treatment. Please cpntinue as prescribed.
I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
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User feedback


FAQs

Is Zoladex LA 10.8mg Injection chemotherapy?

Zoladex LA 10.8mg Injection is a chemotherapeutic agent used in the treatment of hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, it is used in assisted reproduction and in the treatment of precocious puberty

What is Zoladex LA 10.8mg Injection implant?

Zoladex LA 10.8mg Injection implants contain the active ingredient Zoladex LA 10.8mg Injection acetate and are injected under the surface of the skin on the stomach

How long can I take zoladex for?

It is given once or multiple times as required. Please consult your doctor before taking the drug

Can I take paracetamol/ibuprofen/noethisterone with zoladex?

Yes you can take paracetamol/ibuprofen/noethisterone with zoladex.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Goserelin acetate. Luton, Bedfordshire: AstraZeneca UK Limited; 2001 [revised 24 Jan. 2017]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  2. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
  3. UpToDate. Goserelin: Drug information. [Accessed 25 Jun. 2019] (online) Available from:External Link
  4. OncoLink. Goserelin Acetate. [Accessed 25 Jun. 2019] (online) Available from:External Link

Marketer details

Name: AstraZeneca
Address: Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
Country of origin: India
Expires on or after: February, 2025

A licensed vendor partner from your nearest location will deliver Zoladex LA 10.8mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

2851028890Get 1% OFF
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Get this discount by applying coupon 1MGALL on the cart. Max. coupon discount is ₹380. T&C apply.
1.0 Injection in 1 prefilled syringe
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Not returnable Read policy

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