Prugonist 2 Tablet is a prescription medicine used in the treatment of constipation. It increases the release of certain chemical that improves the movement of food inside the intestine and helps to increase gastric emptying of both liquid and solid.

Prugonist 2 Tablet is used in the treatment of chronic constipation and irritable bowel syndrome

Uses of Prugonist Tablet

Treatment of Constipation

Benefits of Prugonist Tablet

In Treatment of Constipation

Prugonist 2 Tablet helps to stimulate bowel movements. It increases the movement of the intestines, this helps empty your bowels and relieve constipation. Emptying of both solid and liquid wastes relieves the pain and discomfort caused due to constipation and improves your quality of life. Eat more high-fiber foods including fruit and vegetables and drink plenty of water to prevent constipation from happening.

Side effects of Prugonist Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prugonist

Headache
Nausea
Diarrhea
Abdominal pain
Decreased appetite
Dizziness
Indigestion

How to use Prugonist Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prugonist 2 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Prugonist Tablet works

Prugonist 2 Tablet is a selective 5-HT4 receptor agonist that has high intrinsic activity. It indirectly stimulates the release of acetylcholine, a chemical messenger that increases the motility of the intestine and treats even chronic (long-term) constipation very effectively.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Prugonist 2 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Prugonist 2 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Prugonist 2 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Prugonist 2 Tablet may cause side effects which could affect your ability to drive.
Prugonist 2 Tablet may cause dizziness and tiredness, especially on the first day of treatment, and this may have an effect on driving and use of machines.

Kidney

CAUTION

Prugonist 2 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Prugonist 2 Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Prugonist 2 Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Prugonist 2 Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Prugonist 2 Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

What if you forget to take Prugonist Tablet?

If you miss a dose of Prugonist 2 Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Prugonist 2 Tablet

₹11.5/Tablet

Pruvict 2 Tablet

Torrent Pharmaceuticals Ltd

₹33.45/tablet

191% costlier

Presmovac 2 Tablet

Torrent Pharmaceuticals Ltd

₹15.3/tablet

33% costlier

Consticalo 2 Tablet

Torrent Pharmaceuticals Ltd

₹15.2/tablet

32% costlier

Pioride 2mg Tablet

Alembic Pharmaceuticals Ltd

₹13.7/tablet

19% costlier

Pruease 2mg Tablet

Sun Pharmaceutical Industries Ltd

₹15/tablet

30% costlier

View all substitutes

Quick tips

Prugonist 2 Tablet helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
It can be taken with or without food, at any time of the day.
It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
Inform your doctor if your constipation has not improved even after four weeks of taking this medication.

Fact Box

Chemical Class

Dihydrobenzofurancarboxamide Derivative {benzamides}

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin (5-HT4) receptor agonist-Prokinetic agent

Patient concerns

1.5 month paignant.visit with BT Nw filling pain on belly.why this pain is she feeling. My wife filling pain on lower abdomen

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Does she have constipation

My maximum result was in my constipation condition.in that case, when i pressurise for bowel excreate then automatically a drop of white discharge come out through penis

Dr. Praveen Pushkar

Urology

Its normal avoid constipation

FAQs

How quickly does Prugonist 2 Tablet work?

Prugonist 2 Tablet has been found to act rapidly but the effect varies from person to person. This is because the response to a particular medication varies in every patient. Usually, the medicine generates a bowel movement within 2-3 hours. However, it may take about 4-5 days to show complete effect and rapid bowel movements.

Is Prugonist 2 Tablet safe in pregnancy?

No, Prugonist 2 Tablet is not safe to be taken during pregnancy. There are few reported cases of spontaneous abortion that have been noted when given in pregnant women. There is little evidence of use of Prugonist 2 Tablet in pregnant women. Therefore, its use during pregnancy should be avoided. It is important to consult your doctor before starting this medication.

When should I take Prugonist 2 Tablet?

Prugonist 2 Tablet can be taken at any time of the day. Normally, it is taken orally with or without food once daily. The exact dosage of this medication is to be decided by your prescribing physician. Usually, it is taken as 2 milligrams per day.

Can Prugonist 2 Tablet cause gastroparesis?

Prugonist 2 Tablet has been proven to be beneficial in cases of gastroparesis and constipation. Gastroparesis is a condition where there is reduced movement of the gut that leads to delayed emptying of the stomach and constipation. Generally, this occurs in conditions like diabetes or after surgery.

When should I avoid taking Prugonist 2 Tablet?

You should avoid taking Prugonist 2 Tablet if you are allergic to it. It should also be avoided if you have a tear in your stomach or intestinal wall, a bowel blockage or inflammatory conditions of the intestinal wall like Crohn’s disease or ulcerative colitis. Always consult your doctor before starting the medication. The doctor should be informed about any ongoing medication and conditions you have.

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References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1327.
Prucalopride succinate. London, England: Shire Pharmaceuticals Limited; 2009 [revised 27 May 2015]. [Accessed 28 Jan. 2019] (online) Available from:
Prucalopride. Baggot Street Lower Dublin: Shire Pharmaceuticals; 2009 [revised Mar. 2019]. [Accessed 28 Mar. 2019] (online) Available from:
Prucalopride [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2020. [Accessed 05 Aug. 2023] (online) Available from:

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