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MD (Pharmacology), MBBS
Last updated
13 Mar 2024 | 04:45 PM (IST)

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Ributin Capsule

Prescription Required
Marketer
SALT COMPOSITION

Product introduction

Ributin Capsule is an antibiotic, used in the treatment of tuberculosis with HIV (human immunodeficiency virus) infection. It helps to fight germs (bacteria) called mycobacteria, which cannot be destroyed by other antibiotics in people who have a weaker immunity.

Ributin Capsule may be used alone or in combination with other medicines to help prevent serious infections caused by microorganisms like mycobacterium avium complex (MAC). It should be taken in the dose and duration as advised by the doctor. This medicine should be taken on an empty stomach. It is better to take it at the same time each day to get the most benefit and you should keep on taking this medicine for as long as you are prescribed. Stopping it early may make the infection to come back and harder to treat.

Some people may develop side effects like decreased white blood cells, anemia, rash, nausea, and fever. These side effects are usually temporary and go away during treatment as your body adjusts to the medicine. Consult your doctor if these side effects bother you or do not go away.

Before starting treatment with this medicine, you should tell your doctor if you are pregnant, breastfeeding, or suffering from any liver, kidney, or heart problems or if you are allergic to any medicine. You may be regularly monitored with blood tests and chest x-rays to check that you do not have active tuberculosis or any other mycobacterial disease. Your doctor may advise for regular eye examination and liver function tests while using it.

Uses of Ributin Capsule


How to use Ributin Capsule

Take this medicine in the dose and duration as advised by your doctor.

How Ributin Capsule works

Ributin Capsule works by inhibiting an enzyme DNA-dependent RNA polymerase in bacteria, leading to the suppression of RNA synthesis that is required for survival and this leads to cell death of infection-causing bacteria. This helps treat Mycobacterium avium complex disease (tuberculosis) in patients with human immunodeficiency virus (HIV) infection.

Safety advice

Alcohol
There is no data available. Please consult doctor before consuming the drug.
Pregnancy
There is no data available. Please consult doctor before consuming the drug.
Breast feeding
There is no data available. Please consult doctor before consuming the drug.
Driving
There is no data available. Please consult doctor before consuming the drug.
Kidney
There is no data available. Please consult doctor before consuming the drug.
Liver
There is no data available. Please consult doctor before consuming the drug.

What if you forget to take Ributin Capsule?

If you miss a dose of Ributin Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Ributin Capsule is used to treat tuberculosis in patients with HIV.
  • Seek immediate medical attention if you develop sudden wheeziness, difficulty in breathing, pain in the chest, swelling of eyelids, face, or lips, rash or itching.
  • Taking Ributin Capsule may change the color of your urine to red/orange. You may also experience coloring of the skin and other body fluids and also of soft contact lenses.
  • You may be regularly monitored with blood tests and chest X-rays to check that you do not have active tuberculosis or any other mycobacterial disease.
  • You may also undergo regular eye examinations while using Ributin Capsule.
  • Use non-hormonal birth control techniques (condom, diaphragm with spermicide) to prevent pregnancy, as Ributin Capsule can make birth control pills less effective.

Fact Box

Chemical Class
Macrolactams
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
RNA polymerase inhibitors- Rifamycins

Patient concerns

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Dr. Megha Gupta
Obstetrics and Gynaecology
Such problems are common after getting ovaries removed. Do not worry, these problems will eventually fade with time. However if it causes discomfort and restlessness, you should see your gynaecologist for hormonal replacement therapy
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Dr. Shubhra Chandhan Pradhan
ENT
It may be a lipoma or lymph node. Do a FNAC

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Gumbo T. Chemotherapy of Tuberculosis, Mycobacterium Avium Complex Disease, and Leprosy. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1550-554.
  2. Chambers HF, Deck DH. Antimycobacterial Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 829.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1212-13.
  4. Rifabutin. Sandwich, Kent: Pfizer Limited; 2003 [revised Dec. 2015]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  5. Medscape. Rifabutin. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:External Link

Marketer details

Name: Lupin Ltd
Address: Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India .
Country of origin: India

NOT FOR SALE
We do not facilitate sale of this product at present

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