Endomysial Antibody Test (IgA) - IFA In Dilutions
Understanding Endomysial Antibody Test (IgA) - IFA In Dilutions
What is Endomysial Antibody Test (IgA) - IFA In Dilutions?
This test helps in:
1) Diagnosis of dermatitis herpetiformis and celiac disease.
2) Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease
3) Obviate the need for multiple small bowel biopsies to verify the diagnosis. This may be particularly advantageous in the pediatric population, including the evaluation of children with failure to thrive.
Interpreting Endomysial Antibody Test (IgA) - IFA In Dilutions results
Interpretations
If the results of the EMA blood test are negative, it clearly means there were no EMA antibodies present in the blood. A result portraying the absence of endomysial antibodies does not, however, confirm the absence of dermatitis herpetiformis or celiac disease. Even those who have mild gluten-sensitive enteropathy could have a negative EMA test.
Circulating IgA endomysial antibodies are found in close to 70% to 80% of patients with dermatitis herpetiformis or celiac disease. In case the blood tests show a high level of IgA EMA and tTG antibodies, it could be an indicator of celiac disease.